For years, Big Pharma has kept an eye on mRNA gene transfer technology. In 2019, a Milken Institute panel specifically discussed how to transition from conventional vaccine development to novel mRNA technology.
The Worst Design Failure in the History of Medicine
Participants included Anthony Fauci, Ph.D., director of the National Institutes of Allergy and Infectious Diseases (NIAID), and Rick Bright, Ph.D., former director of the U.S. Biomedical Advanced Research and Development Authority (BARDA), now senior vice president of pandemic prevention and response at the Rockefeller Foundation.
Bright suggested, “There may be a need, even an urgent call, for an exciting facility out there that is completely unconventional and doesn’t adhere to bureaucratic guidelines and processes.”
Reading between the lines, it sounds like Bright is suggesting that a pandemic might help them make this risky transition, since bypassing “bureaucratic strings and processes” would likely be more acceptable in the face of an acute crisis.
Well, it looks like Bright and Fauci got their wish, and the world’s population is paying the price for their decision to throw bureaucratic rules and procedures and the precautionary principle to the wind. Many doctors and scientists warned that mRNA-based “vaccines” were ill-advised and premature.
Now, a year after their disastrous introduction, we are finding out how little scientists know about these vaccines. Or worse, they know and don’t care about the harm they cause.
In an August 20212 Substack article, British cybersecurity researcher Ehden Biber examined how the mRNA syringes were made and came across what he called “the worst design flaw in human history.”
The COVID syringes do not contain the identical mRNA found in the SARS-CoV-2 virus. The mRNA has been genetically engineered in a process called “codon optimization,” and this process is known to cause completely unanticipated side effects. “How is it that Prizer, Moderna, AstraZeneca, Janssen, etc. are using a technology that both they and regulators know will lead to unknown outcomes?” asks Biber. Here’s an excerpt from that eye-opening article:
Trying to tell the body to make protein is difficult for many reasons. One of them is the fact that trying to run the protein information through ribosomes, which process that code and create the protein, can be very slow or get stuck during the process.
Fortunately, scientists have found a way to overcome this problem by performing a code substitution: Instead of using the original genetic code to create the protein, they changed the letters in the code so that the code was optimized. This is known as codon optimization.
Codons are three nucleotides; nucleotides are the building blocks of DNA. Here is an example of codon optimization: 60% of the codons were changed, 22% of the nucleotides were changed. And yet the end result is that the ribosomes produce the same protein! The same? Well, not quite.
In 2011, the journal Nature Medicine published an article titled “Breaking the Silence.” It described how codon optimization, which uses these synonymous DNA changes, can cause disease in different ways.
It turned out that the protein produced in codon optimization folds differently and has a different 3D shape, and that this “could, for example, cause immunogenicity that would not be detected until late clinical trials or even after approval. This statement refers to the NORMAL approval cycle. The COVID vaccines were approved under an expedited process.
Beavers cites a quote from Chava Kimchi Sarfaty, Ph.D., a principal investigator at the U.S. Food and Drug Administration: “We don’t think you can tweak codons and have the protein behave the way it did in its original form.”
In summary, codon optimization can change the way proteins fold and function, and Sarfaty cautioned, “The altered shape could, for example, cause immunogenicity that would not be apparent until late in clinical trials or even after approval. If the FDA knew all this back in 2011, why didn’t it object to codon optimization in the manufacture of COVID vaccines?
Protein Misfolding Linked to Many Diseases
Biber cites a number of studies linking protein misfolding to a range of serious diseases, including neurodegeneration in Alzheimer’s disease, Parkinson’s disease, and heart failure. As explained in the 2017 publication, “Protein Misfolding Diseases:
Most protein molecules must fold into defined three-dimensional structures to acquire functional activity. However, protein chains can assume a variety of conformational states, and their biologically active conformation is often only marginally stable.
Metastable proteins tend to populate misfolded species that tend to form toxic aggregates, including soluble oligomers and fibrillar amyloid deposits, which have been linked to neurodegeneration in Alzheimer’s and Parkinson’s disease and many other pathologies.
“If it’s so problematic, why are manufacturers using it?” asks Biber. The answer is that they need higher protein expression than is possible naturally for the injection to work.
In its BNT162b2/Comirnaty risk management plan submitted to the FDA to obtain emergency approval, Pfizer admits that the codon optimization performed resulted in increased gamma-glutamyl transferase (GGT), which is an early marker of heart failure.
Pfizer appears to have been most aggressive in its codon optimization, and it is no secret that the severe alteration of mRNA can lead to protein misfolding and “splicing abnormalities.” A March 2021 paper states:
The BNT162b2 vaccine against COVID-19 consists of an RNA with 4284 nucleotides divided into six segments that provide the information for the production of S-spike proteins used by SARS-CoV-2 … to infect the host. Then, these proteins are directed out of the cell and trigger the immune response and antibody production.
The problem is the severe alteration of the mRNA: uracil is replaced by pseudouridine to deceive the immune system; the letters of all codon triplets are replaced by a C or a G to extremely increase the rate of protein synthesis; some amino acids are replaced by proline; a sequence (3′-UTR) with unknown alteration is added…
Any mistranslation has implications for the pathophysiology of a variety of diseases. In addition, the injected mRNA is pre-mRNA that can lead to multiple mature mRNAs; these are alternative splicing abnormalities that can cause severe long-term damage to human health.
These are alternative splicing abnormalities that are a direct cause of serious long-term damage to human health, even though the DNA is not altered but is located in the nucleus rather than in the cytoplasm where the altered mRNA arrives.
Pfizer Vaccine Raises Markers for Early Death
In its risk management plan for BNT162b2/Comirnaty, submitted to the FDA to obtain emergency approval, Pfizer even admits that the codon optimization they performed resulted in elevated gamma-glutamyl transferase (GGT), which is an early marker of heart failure.
Elevated GGT levels are also an indicator of insulin resistance, cardiometabolic disease, liver disease, and chronic kidney disease. If your GGT levels are elevated, it also means your liver is under stress. The ideal GGT level is below 16 units per liter (U/L) for men and below 9 U/L for women. Levels higher than 25 U/L for men and 18 U/L for women significantly increase your risk for chronic disease.
In addition, as GGT levels increase, glutathione levels also decrease. This is part of the equation that explains how elevated GGT is detrimental to your health. If you increase your glutathione level, your GGT level will decrease.
Although Pfizer acknowledges these risks, the company has not conducted studies to evaluate pharmacological safety, genotoxicity or carcinogenicity. “How did they manage to avoid testing?” asks Biber. The answer is downright shocking.
Crucial Studies Have Been Skipped
Under normal circumstances, studies on pharmacological safety, genotoxicity or carcinogenicity are conducted as part of animal testing. No animal studies were conducted for the COVID vaccine; consequently, none of these studies were conducted, period. Thanks to the expedited process, mRNA vaccines have been used directly in human studies. And the FDA apparently has no intention of requiring Pfizer to study the health effects of its codon optimization. As Beavers notes:
Manufacturers know about the potential risk. Regulators know about the potential risk. Yet regulators do not test V products as gene therapy and do not implement a codon optimization risk mitigation plan. IF YOU DON’T MEASURE THE RISK, IT DOESN’T GO AWAY.
It is simply amazing that they have distributed these syringes to billions of people worldwide, knowing full well that the syringes can cause serious problems.
Another problem raised in Biber’s article is that cell types vary widely in their coding, so determining how mRNA is translated in one tissue type says nothing about translation kinetics in another. None of the COVID manufacturers have tested their product on all available tissue types (51 in total).
Translation kinetics can lead to translation pauses, which can play a role in modulating protein conformation, lead to structural changes, increase immunogenicity, and alter performance. This has been reported since the 1990s. Sure, right?” writes Biber.
To summarize succinctly: Pfizer, Moderna, and Janssen have altered the genetic code of their RNA to ensure that the resulting spike protein your body makes is more stable, and to bypass the protective mechanisms in cells that prevent viral replication.
Without this change, your immune system would simply destroy the mRNA before your cells could start producing spike protein. The problem is that this codon optimization, this genetic rewriting, leads to translation errors when your ribosomes – the “machines” in your cells that synthesize proteins – process the code.
These translation errors can lead to misfolded and poorly functioning proteins. We already know that some misfolding of proteins is associated with neurodegenerative diseases and sudden heart failure. But we have no idea what the misfolded proteins resulting from COVID vaccination might do. The consequences could be identical to those of other protein misfoldings, or they could lead to entirely new conditions.
To learn more, be sure to listen to the “Planet Lockdown” interview with Alexandra Henrion-Caude, Ph.D., a geneticist and researcher at the French Institute of Health, found at the top of this article. She explains what RNA is, how COVID vaccination is theoretically supposed to work, and what concerns there are about its use.
She points out that if you wanted to make a vaccine, you wouldn’t target the part of the virus that is most susceptible to mutation (the spike protein). One would choose a part of the virus that is less prone to mutation. By focusing on the spike protein, one was forced to make multiple vaccines to keep up with mutations.
By choosing the spike protein as a target, the body was also programmed to produce the most toxic part of the virus. We know that the spike protein alone is pathogenic, causing blood clots and abnormal bleeding, for example – even without the rest of the virus. The blood clotting and/or bleeding is due to your immune system attacking and destroying the cells in your vascular system that produce the spike protein.
What Can You Do If You Have Been Infected with COVID?
As mentioned earlier, because of the modification of the spike protein mRNA used in the vaccine to make it more “effective,” translation errors can lead to misfolded proteins with very serious health complications.
Fortunately, your body has a process to correct this misfolding because about one-third of the proteins your body makes are already misfolded when they are made.
There are two simple strategies you can use to specifically refold or eliminate these proteins. The first one I’ve talked about frequently in the past is the time-restricted diet, where all meals are eaten within a six to eight hour window that ends at least three hours before bedtime. This stimulates a process called autophagy while you sleep and in the morning, when your fasting period extends beyond 14 hours.
The second, lesser-known strategy is regular sauna bathing. When the sauna is hot enough, your body creates heat shock proteins that refold or eliminate misfolded proteins. You just need to make sure it’s hot enough and that you’re sweating really hard. Biometrically, you can measure by raising your temperature to about 101 to 102 degrees Fahrenheit (about 39 °C) with an oral thermometer.
Also, you will probably lose 1 to 2 pounds (0.91 kg) through sweat. Be sure to drink enough water and replace the salt you lose. In addition, many saunas are exposed to high electromagnetic fields (EMF), so choose your sauna carefully. Many new infrared saunas have eliminated magnetic fields, but virtually all have high electric fields that can be problematic.
Moral Pills to Suppress Dissent?
Based on what we already know, there is clearly cause for great concern about COVID vaccines. It seems undeniable that they can cause very serious health problems, both acutely and in the long term. Nevertheless, vaccine manufacturers, national health authorities, and politicians are urging that every man, woman, and child be vaccinated multiple times.
There is simply no doubt that COVID vaccinations are the largest human experiment in history. The effects are already beyond devastating, but we really have no idea what the full extent will be.
The same is true for every other pandemic measure, from general masking to social distancing to lockdowns. None of these measures have scientific evidence of their effectiveness, and we have only scratched the surface when it comes to assessing the damage they have caused.
To quell opposition to these unethical experiments on the public, at least one person has proposed an outrageously radical idea: “moral pills.” Basically, the idea is to use drugs to make the population compliant. As Forbes reported in August 2020:
…Bioethicist Parker Crutchfield has proposed a controversial approach to combating the pandemic – namely, a ‘moral pill.’ Specifically, he suggests that widespread administration of psychotropic drugs could provide a ‘moral boost’ that would make people more likely to adhere to social norms such as wearing masks and following social distancing guidelines …
Crutchfield [notes] that those in need of moral upgrading are also the least likely to opt for it. He therefore explores involuntary methods, such as the legal requirement to take the morality pill or the clandestine administration of the drug through the water supply.
In other words, making it mandatory to take a “morality pill” does not change the basic moral calculus of the proposed policy. It merely makes it easier for authorities to enforce good (or bad) laws.
Crutchfield’s proposal seems straight out of a dystopian novel, but it fits well with technocratic ideology, which basically says that technocrats – a small, powerful elite who believe they can achieve immortality through transhumanism – are smarter and more worthy of life than everyone else and therefore have the right to dictate moral truth to the masses.
Editor’s Note: After widespread criticism of his commentary on Crutchfield’s moral pills, Forbes in February 2022 changed the article’s headline to “No, Don’t Use a ‘Moral Pill’ to Stop the COVID Pandemic” and added an author’s note explaining that the headline was changed to “more clearly represent” the author’s personal position.
In the Hunt for a Universal Super-Syringe Agent
Many experts now admit that the pandemic is over, but the pandemic industrial complex isn’t ready to let go of its brand-new golden goose. As discussed at the 2019 Milken Institute meeting, they are on the hunt for universal mRNA-based “super shots.”
In 2019, Fauci focused on a universal flu vaccine. Today, the goal is a universal COVID vaccine that protects against both old and new strains. One way to achieve this might be to target the nucleocapsid protein (n-protein) that is inside the virus, rather than the spike, as is currently the case.
By targeting a part of the virus that changes little from one strain to the next, one could achieve broader protection. The question is why hasn’t this been done from the beginning? Or – perhaps the better question should be: Does this have anything to do with the “promising” mRNA HIV vaccine that NIAID Director Dr. Anthony Fauci announced in December 2021?
As co-author of the research paper on this vaccine, Fauci explained that it works like the COVID mRNA vaccine but does not contain spike protein instructions. Rather, it provides coded instructions to get two key HIV proteins to produce virus-like particles of themselves in muscle cells.
Whatever the reason for how the upcoming HIV mRNA vaccine works, despite decades of effort, all polyvalent vaccines have failed. Given the careless approach to the current COVID vaccines, one has to wonder if vaccine developers and regulators can be trusted to produce a safe and effective polyvalent vaccine.
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