Earlier this summer, a June 18, 2020 report personally authored by Dr. Juan F. Gastón Añaños of the Pharmaceutical Department of the Spanish Hospital in Barbastro (Huesca province), titled: “Links and Possible Causes of the Pandemic with the Updated Influenza Vaccine.”
A Report that Appears and Disappears, only to Return Altered
Raising questions about the link between the seasonal flu vaccine and deaths attributed to Covid-19, particularly among our elderly.
Amazingly, the link to the original report (June 18, 2020) has been nowhere to be found since June 28, except on Wayback machine. This service scans the web continuously and keeps “images” of what is published. This allows, in case of deletion, to find most of the articles. Except of course in case of a more thorough cleaning of the internet memory.
Published on June 28, 2020, it was deleted the next day on the site elarconte.com, however we can find it through the web archives. It was then modified on June 29, 2020 and republished without specifying the modifications made.
Nevertheless, it is likely that this modification is related to a denial article from the Spanish Vaccination Association (AEV), which categorically denies the information about the association between polysorbate 80 (flu vaccine) and SARS-CoV-2 infection. A microbiology expert tells us: “this denial was unconvincing”.
And she adds, “yet this theoretical study concluded to hypothesize a possible theoretical immunological interference mechanism to explain that patients who get sick with COVID-19 and received the flu vaccine die more than patients with COVID-19 who were not vaccinated against influenza in the last campaign in this province of Spain, focusing on an adjuvant (excipient), Polysorbate 80, for which there are described adverse immunological reactions.”
Interference exists between various Viruses
On September 15, a publication in Nature, which seems to have gone unnoticed, focused on the interference between rhinoviruses (coronaviruses of mild colds) and the influenza A virus (IAV), i.e. H1N1, responsible for the 2009 pandemic. Let us recall here that the seasonal flu virus is also an influenza virus.
The authors performed a retrospective analysis of clinical data (1) and an experimental study (2) to investigate :
– the co-occurrence of rhinoviruses and para- and influenza viruses in adults older than 21 years in the USA tested by Multiplex PCR during 3 seasons from November to March 2016-17, 207-19, and 2018-19 and compare what was observed versus what was expected (1).
– Interference between these 2 types of viruses, by experimental infection of respiratory epithelium cell cultures with H1N1 and then with rhinovirus followed by sequential quantification of infection in the presence or absence of an inhibitor of interferon production (2).
Their observations led to the hypothesis that a single respiratory virus can block infection by another through the stimulation of anti-viral defenses (in this case, interferon production by induction of ISG gene expression) by the respiratory mucosa.
This could explain the idea that interference between H1N1 and seasonal rhinoviruses would have allowed the 2009 epidemic to be extinguished and that this hypothesis should be considered for intervention strategies between seasonal influenza epidemics in the presence of the current SARS-Cov2 “pandemic. In other words, seasonal rhinoviruses (common coronaviruses), by competing with seasonal influenza, could function as protectors by blocking infection by other more pathogenic respiratory viruses, and would allow the extinction of the latter every year. To this competition, another coronavirus, the SARS-CoV2, is now added, which by extrapolation of these conclusions, could also participate in the extinction of the seasonal flu epidemic, and vice versa.
Here the subject is not cross immunity, since influenza and colds do not belong to the same family of viruses (influenza and coronavirus, respectively), but the triggering of the production of interferon, a glycoprotein of the cytokine family, a powerful antiviral naturally produced by the cells of our immune system and by other cells, including the cells of the respiratory epithelium. In other words, the complex but exceptionally adaptive functioning of our immune system.
Flu Caccination studied has an association with Covid 19 Virus
Most recently, an October 1, 2020, scientific publication examined the potential association between influenza vaccination rates and Covid-19 deaths in 39 countries around the world with populations of more than half a million people among the elderly. (See Attachment at the End)
The results showed a positive association between covid-19 deaths and seasonal influenza vaccination rates among people aged 65 and older, with a significant increase in covid-19 deaths from eastern to western regions of the world. In plain English, this means that older people who had been previously vaccinated against influenza were more likely to die from Covid-19 than those who had not been vaccinated.
Again, the author concludes that more research is needed to explain these observations and prevent these potential Covid-19-related deaths.
There is agreement that an alleged link between the administration of a seasonal influenza vaccine and “confirmed” cases of COVID-19 that have resulted in death needs to be urgently investigated. Was the release of the SARS-CoV2 deaths (by testing almost no one at the time and automatically attributing them to COVID-19) intended only to muddy the waters and reduce the correlation between the two diseases? Failure to eliminate this possible causal link would seem to put the public at risk for the next (upcoming) flu vaccination campaign, which could be associated with a new severe epidemic of this virus, or even a resurgence and many more deaths.
On October 3, the Administrative Court of the Lazio Region (Italy) overturned the April 17 order of the President of the Lazio Region, Nicola Zingaretti, imposing mandatory vaccination against seasonal influenza for all persons over 65 years of age. Did he know about this study?
Considering all this, and at a time when many doctors are calling for us all to be massively vaccinated against the flu, this study would allow us to define a vaccination strategy with a targeted population in relation to the flu: Perhaps it would be better to prioritize vaccinating children (as mentioned by Professor Raoult, as well as the pneumococcal vaccine) rather than their grandparents, in order to limit the chains of transmission of the flu and thus preserve the defensive capital of our elders against the covid-19, so that they no longer die from it?
One Physician tells us:
“This position will certainly be debated and misunderstood because if we vaccinate children, the elderly will not be infected with the influenza virus and therefore will not benefit from the interference between influenza and coronavirus through the release of interferon. Thus, the problem would not be the vaccine itself, but the fact that it “deprives” people (children and elderly alike) of influenza infection.”
A more complex analysis of this issue arises from the effectiveness of the influenza vaccine and the vaccination coverage rate. Vaccine effectiveness depends on which strains of virus it targets and how the virus mutates. Since population vaccination coverage is never 100%, there is always doubt about the spread of the virus and the limitation of target groups according to vaccination coverage. We would not necessarily prevent vaccinated people from contracting the virus, but we would allow this flu to be attenuated or even pass unnoticed. So we are limiting the transmission chains.
Moreover, numerous scientific publications show that T-cell activation (cell-mediated immunity) plays a more important role than specific antibodies (humoral immunity) in fighting SARS-CoV2 infection and is involved in cross-immunity. Wouldn’t it therefore make more sense to boost this natural immunity, which declines in older people as they age, for example with the help of vitamin D and zinc supplements (which they often lack), but also with vitamin C?
A global reflection on the strategy of anticipation of people at risk, including the elderly, in the face of Covid-19 is urgently needed!
Positive Association between COVID-19 Deaths and Influenza Vaccination Rates