MIT scientist Stephanie Seneff’s paper, “Worse Than the Disease: Reviewing Some Possible Unintended Consequences of mRNA Vaccines Against COVID-19,” published in the International Journal of Vaccine Theory, Practice and Research in collaboration with Dr. Greg Nigh, remains one of the best and most comprehensive descriptions of the many possible unintended consequences of mRNA gene transfer technologies mislabeled as “COVID vaccines.”
An Insanely Ruthless Process
On December 9, 2021, her article was reprinted in the Townsend Letter, the Examiner of Alternative Medicine. Dr. Seneff, a senior research scientist at MIT for more than five decades, has spent much of her career studying the dangers and mechanisms of action of glyphosate.
Her attention was drawn to the science of mRNA gene transfer technologies in early 2020, when Operation Warp Speed was announced. As she noted in her paper, there were many factors for which there was no precedent, but which were implemented at breakneck speed, including:
- The first use of PEG in an injection.
- The first use of mRNA gene transfer technology against an infectious agent
- The first-ever “vaccine” that makes no clear claims about reducing infection, transmissibility or death
- The first-ever coronavirus vaccine tested in humans (and previous coronavirus vaccines all failed due to antibody-dependent boosting, a condition in which antibodies promote rather than repel infection)
- The first use of genetically engineered polynucleotides in the general population.
In a May 2021 interview with me, Seneff said:
To develop this incredibly new technology so quickly and skip so many steps in evaluating [safety], that’s insanely reckless. My instincts told me this was bad, and I needed to know [the truth].
So I dug into the research literature of the people who developed these vaccines, and then into more advanced research literature on these topics. And I don’t see how these vaccines can do any good ….
At the time, just five months after the mass vaccination campaign began, Seneff suspected that the COVID vaccines would end up killing far more people than the infection itself. Today, a full year later, the statistics are beyond grim, proving that her educated prediction was correct.
mRNA Vaccines are shockingly Dangerous
As of December 3, 2021, the U.S. Vaccine Adverse Event Reporting System (VAERS) has recorded the staggering number of 927,738 adverse events associated with COVID vaccines, including 19,886 deaths. VAERS may receive reports from vaccine manufacturers and other international sources, and if we exclude these, the number of deaths reported exclusively in U.S. territories is 9136.
Of the total reported deaths, the vast majority are accounted for by Pfizer-the only company granted a full license by the U.S. Food and Drug Administration for a COVID vaccine that is not yet available-13,268, compared with 4,894 for Moderna, 1,651 for Janssen, and 73 for an unnamed brand.
Pfizer also accounts for the vast majority of post-injection hospitalizations, and while those over 66 account for the majority of deaths, the 25- to 50-year-old age group accounts for the majority of hospitalizations. Major side effects now being reported in large numbers include:
- Heart problems such as myocardial infarction and myopericarditis
- Thrombocytopenia (low platelet count)
- Bell’s palsy
- A variety of permanent disabilities, many of which involve neurological dysfunction
All of these consequences were predicted by Seneff and Nigh in their work, which makes the events all the more tragic. Importantly, VAERS is notoriously underreported, so the real-world impact of these injections is far greater than these data suggest.
The Cure Is Actually Worse Than the Disease
Calculations by Steve Kirsch, executive director of the COVID-19 Early Treatment Fund, and his team of statisticians suggest that VAERS reports associated with COVID are underreported by a factor of 41. This is a conservative estimate supported by calculations using a variety of sources in addition to VAERS itself.
This means that the actual number of deaths in the U.S. alone (using data for U.S. territories only) is more likely to be 374,576 (including international deaths reported to VAERS, the number of deaths would be 815,326), and these are deaths that occurred within days or weeks of injection.
As Seneff and Nigh explain in their paper, there are overwhelming reasons to suspect that these gene transfer injections will have devastating long-term effects and lead to an excess of deaths over the next decade.
Moreover, it is clear that the number of deaths from COVID-19 infection, even in the U.S., is greatly exaggerated based on positive PCR tests and even mere suspicion of COVID when no testing was done. Many died of other causes and just happened to have a positive COVID test at the time of death.
Kirsch estimates that the actual number of deaths from COVID-19 is about 50% of the reported number (which is probably conservative). This means that about 380,000 Americans have died from COVID-19 (rather than COVID), while COVID vaccinations may have claimed more than 374,570 lives in the first 11 months alone.
Seneff suspects that over the next 10 to 15 years, there will be a dramatic increase in prion diseases, autoimmune diseases, neurodegenerative diseases at younger ages, and blood diseases such as blood clots, hemorrhages, strokes, and heart failure.
As predicted in the title of Seneff’s paper, it appears that the cure may end up being worse than the disease. This is especially true for children and young adults, thousands of whom have died or been permanently disabled by the vaccines, while the risk of dying or being seriously harmed by the infection itself is extraordinarily low.
Seneff suspects that in the next 10 to 15 years there will be a dramatic increase in prion diseases, autoimmune diseases, neurodegenerative diseases at younger ages, and blood diseases such as blood clots, bleeding, strokes, and heart failure.
The Spike Protein is the Most Dangerous Part of SARS-CoV-2
The reason the COVID vaccine is causing all these problems is that it is causing cells to continuously produce SARS-CoV-2 spike protein, which we now know is the most dangerous part of the virus. Many experts have noticed this from the beginning and wondered what the vaccine developers were thinking in choosing this antigen for their vaccines.
While the mRNA injections can cause harm in many different ways, a fundamental problem is that they can overstimulate the immune system to the point of failure. As your cells begin to produce the viral spike proteins, your immune cells rush to scoop up the proteins and funnel them into your lymphatic system. (This is why many report swollen lymph nodes under their arms).
The antibody response is part of humoral immunity. You also have cellular immunity, which is part of your innate immune system. Your innate immune system is very powerful. When you are healthy, it can eliminate viruses without ever producing a single antibody. Antibodies are actually a secondary effect when your innate immune system fails.
The problem is that your innate immune system is not activated and probably cannot protect you when you get a COVID-19 shot because all the areas where your innate immune system would come into play are bypassed.
Normally, you breathe in the virus and stimulate the production of secretory IgA antibodies that protect your respiratory system. If you bypass this route of exposure with a shot in the arm, no secretory IgA antibodies are produced, leaving you vulnerable to infection.
As Ronald Kostoff explains in an excellent December 8, 2021 article in Trial Site News, “COVID-19 ‘Vaccines’: The Wrong Bomb Over the Wrong Target at the Wrong Time.”
An effective vaccine would focus on cellular immunity in the respiratory and intestinal tracts, where secretory IgA is produced by your lymphocytes, which are located just below the mucous membranes lining the respiratory and intestinal tracts.
The antibodies produced by these lymphocytes are passed through the mucous membranes to their surface. These antibodies are thus on site to encounter airborne viruses, and they can prevent virus binding and cell infection.
Unfortunately, the main inoculants currently used for COVID-19 focus on antibodies (IgG and circulating IgA) found in the bloodstream. These antibodies protect the body’s internal organs from infectious agents that try to spread through the bloodstream.
When you are injected with the COVID vaccine, your body makes only IgG and circulating IgA, not secretory IgA, and these types of antibodies do not effectively protect your mucous membranes from SARS-CoV-2 infection. As Kostoff noted, the breakthrough infections we are now seeing “confirm the fundamental design flaws” of this gene transfer technology.
Natural infection with SARS-CoV-2 (coronavirus) remains confined to the respiratory tract in most people,” Kostoff wrote. “The vaccines currently in use cause cells deep in our bodies to express the viral spike protein, which they were not naturally designed to do.
Any cell that expresses this foreign antigen on its surface is attacked by the immune system, involving both IgG antibodies and cytotoxic T lymphocytes. This can occur in any organ, but the damage is most severe in the vital organs.
We now see that the heart is affected in many young people, leading to myocarditis or even sudden cardiac arrest and death. In other words: We are dropping the wrong bomb on the wrong target at the wrong time!
Eventually, your body will believe that your innate immune system has failed, which means it has to call in the reserve cavalry. Basically, your body is now overreacting to something that isn’t even true. You are not really infected with a virus and your innate immune system has not failed, but your body is forced to react as if both are true.
Long-term lasting Effects More Likely
In addition, the synthetic RNA in the mRNA vaccines contains a nucleotide called methylpseudouridine that the body cannot break down, and the RNA is programmed to trigger maximum protein production. So we are dealing with a completely unproven manipulation of RNA.
It is very important to know that this is a genetically engineered mRNA for the spike protein. It is not identical to the spike protein mRNA that produces SARS-Cov-2. It has been significantly altered to prevent it from being metabolized by your body.
The spike protein that your body produces in response to the COVID-19 vaccine mRNA binds to your ACE2 receptor. This is because extra prolines have been inserted into the genetically engineered new spike protein that prevent the receptors from closing properly, which in turn causes you to downregulate ACE2. That’s one of the reasons for problems like pulmonary hypertension, ventricular heart failure, and stroke.
As noted in a 202011 paper, there is a “central association” between ACE2 deficiency and SARS-CoV-2 infection. People with ACE2 deficiency are more prone to severe COVID-19 infection. Spike protein suppresses ACE2,12 which exacerbates the deficiency. According to Seneff, the gene transfer injections essentially do the same thing, and we still don’t know how long the effect lasts.
The manufacturers initially thought that the synthetic RNA could survive in the human body for about six months. A more recent study found that the spike protein persisted for 15 months in recovered COVID patients.
This suggests that the synthetic and longer-lived mRNA in COVID syringes may trigger spike protein production for at least as long, and probably longer.14 In addition, the number of spike proteins produced by the syringes is far greater than in natural infection.
As Dr. Peter McCullough15 explains, this means that your body will produce spike proteins for at least 15 months after the initial vaccination. However, if you receive shot #2 a few weeks later, spike protein production will continue for 15 months or longer. With syringe #3 six months later, you will produce spike protein for another 15 months.
With regular booster shots, your body may never get rid of the spike protein. All the while, it wreaks havoc on your biology. McCullough compares it to “a permanent installation of an inflammatory protein in the human body,” and inflammation is the cause of most, if not all, chronic disease. There’s no way these gene transfer injections will improve public health. They will decimate it.
Long-term Neurological Damage to be Expected
In her paper, Seneff describes several key features of the SARS-CoV-2 spike protein that suggest it behaves like a prion. This could explain why the vaccines have so many neurological side effects. According to Seneff, because of the changes made, the spike protein produced by COVID vaccination may actually be a prion rather than the spike protein in the actual virus, and a more potent one at that.
You can find a detailed technical description of this process in Seneff’s paper, but the gist is that the COVID-19 shot instructs your body to produce a toxic protein that eventually concentrates in your spleen, from where prion-like protein instructions are sent out that radically increase your risk of developing neurodegenerative diseases.
Lung, Heart and Brain Diseases are Predictable Consequences
Seneff also goes into great detail about how the spike protein acts as a metabolic toxin. While I recommend reading Seneff’s work in its entirety, I have picked out a few key sections below, starting with how the spike protein can trigger pathological damage that leads to lung damage and heart and brain disease:
The picture is now emerging that SARS-CoV-2 has serious effects on the vasculature in multiple organs, including the cerebrovascular system … In a series of publications, Yuichiro Suzuki, in collaboration with other authors, presented a strong argument that the spike protein itself can cause a signaling response in the vasculature with potentially far-reaching consequences.
These authors observed that SARS-CoV-2 induced significant morphological changes in pulmonary vasculature in severe cases of COVID-19 … Moreover, they showed that exposure of cultured human pulmonary artery smooth muscle cells to the S1 subunit of the spike protein of SARS-CoV-2 was sufficient to promote cell signaling in the absence of the other viral components.
Follow-up work showed that the S1 subunit of the spike protein suppresses ACE2, leading to a condition resembling pulmonary arterial hypertension (PAH), a severe lung disease with very high mortality … The “in vivo studies” to which they referred … had shown that the lung injury caused by SARS coronavirus was primarily due to inhibition of ACE2 by the SARS-CoV spike protein, resulting in a large increase in angiotensin-II.
Suzuki et al (2021) subsequently demonstrated experimentally that the S1 component of SARS-CoV-2 virus at a low concentration … activates the MEK/ERK/MAPK pathway and promotes cell growth. They speculated that these effects are not limited to the pulmonary vasculature.
The signaling cascade triggered in the cardiovascular system would cause coronary artery disease, and activation in the brain could lead to stroke. Systemic hypertension would also be predictable. They hypothesized that this ability of the spike protein to promote pulmonary arterial hypertension might predispose patients recovering from SARS-CoV-2 to later develop right ventricular heart failure.
In addition, they suggested that a similar effect might also occur in response to the mRNA vaccines and warned of possible long-term consequences for children and adults who received COVID-19 vaccines based on the spike protein.
An interesting study by Lei et. al. (2021) found that pseudoviruses – spheres decorated with the SARS-CoV-2-S1 protein but containing no viral DNA in their core – caused inflammation and damage in both the arteries and lungs of mice exposed intratracheally.
They then exposed healthy human endothelial cells to the same pseudovirus particles. Binding of these particles to endothelial ACE2 receptors caused mitochondrial damage and fragmentation in these endothelial cells, resulting in the characteristic pathological changes in the associated tissue.
This study highlights that the spike protein alone, without association with the rest of the viral genome, is sufficient to cause the endothelial damage associated with COVID-19. The implications for vaccines designed to induce cells to produce the spike protein are clear and of concern.
COVID Vaccination Activates Latent Viruses
As mentioned earlier, shingles infection is proving to be a common side effect of COVID vaccination, and like the neurologic, vascular, and cardiac damage we observe, activation of latent viral infections has also been predicted.
One reason latent viral infections occur in response to vaccination is that vaccination deactivates the type I interferon pathway. A second reason is that your immune system is overwhelmed trying to deal with the inflammatory spike proteins flowing through your body. Something has to give, allowing latent viruses to break through.
That’s not the end of your potential problems, however, because these co-infections can exacerbate or accelerate other conditions such as Bell’s palsy, myalgic encephalomyelitis and chronic fatigue syndrome.
Herpes viruses, for example, have been implicated as triggers of both AIDS18 and chronic fatigue syndrome. Some research suggests that these diseases only occur when viruses from different families combine and the type 1 interferon signaling pathway is disabled.
Given all this, it seems inevitable that the COVID mass injection campaign will lead to an avalanche of various debilitating chronic diseases in the long run.